Written by Dr.Albana Greca Sejdini, Md, MMedSc
Prostate drugs are the drugs used for the treatment of prostate problems. With aging, there are 3 common prostate problems:
1. Prostatitis or inflammation of prostate gland
2. Enlarged prostate or Benign Prostatic Hyperplasia (BPH)
3. Prostate cancer
As the causes and manifestation of each prostatic problem differ, there are myriad drugs used nowadays for the treatment of prostatic diseases.
The following paragraphs will give you the whole background of prostate drugs.
I. Prostatitis means that there is an inflammation in the prostate gland, which might occur due to infection with bacteria.
Actually, there are four types of prostatitis:
II. Enlarged prostate or benign prostatic hyperplasia (BPH) is abnormal cellular growth (not cancer) of prostatic tissue. Myriad prostate drugs are used for the treatment of BPH.
III. Prostate cancer occurs when abnormal cells undergo uncontrolled growth within prostatic tissue, forming a tumor mass. Usually, this type of abnormal cellular growth is supported by the male sex hormones (androgens), like testosterone and dihydrotestosterone (DHT). Hormone therapy (also known as androgen deprivation therapy (ADT) or androgen suppression therapy), are prostate drugs which can block or prevent the action of androgens.
It is proved clinically that reducing the levels of androgens in the body causes the cancer to shrink or delay its growth. Unfortunately, hormone therapy can’t cure the cancer completely.
In fact, hormone therapy is indicated in certain situations, including:
1- When surgical or radiation treatments fail to cure the cancer, because the cancer starts to metastasize outside the prostate.
2- Recurrent or persistent prostate cancers.
3- Hormone therapy is used as initial treatment combined with radiation therapy.
4- Prior of surgical or radiation treatments to enhance these treatments effects.
Though Orchiectomy or surgical castration is a surgical procedure, its effect resembles the effect of hormone therapy. In this type of surgery, the surgeon excises the testis (where 90% of androgens are formed), thus causing the prostate cancer to shrink or grow more slowly.
Types of prostate drugs used in hormonal manipulation are:
Chemotherapy is indicated when prostate cancer starts to spread or metastasize to other organs or tissues. Chemotherapy involves the use of anti-cancerous drugs, which are injected into a blood vessel or taken orally. These kinds of prostate drugs have the power to destroy the growing cells in the body.
Some of chemotherapy drugs used might include:
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